Showing posts with label XX Anti-Androgen. Show all posts
Showing posts with label XX Anti-Androgen. Show all posts

Monday, October 15, 2007

Merck OVERVIEW SUMMARY


Merck (NYSE: MRK) headquartered in Whitehouse Station, NJ works in in both human and animal health (Merial).

Merck has agreements with:

Neuromed Pharmaceuticals for treatment of pain and neuro disorders

NicOx for the development of antihypertensive drugs

FoxHollow Technologies for atherosclerotic plaque analysis

Ariad Pharmaceuticals for AP23573, an mTOR inhibitor

Sunday, October 14, 2007

AstraZeneca PIPELINE Part I


Note to self: A look at AZ's products and pipline:


Accolate™ (zafirlukast) Accolate™ (zafirlukast) an oral leukotriene receptor antagonist for the treatment of asthma

Arimidex™ (anastrozole) an aromatase inhibitor for use in postmenopausal women with hormone-sensitive early or advanced breast cancer.

Atacand™ (candesartan cilexetil) Phase III for diabetic retinopathy

Casodex™ (bicalutamide) an oral non-steroidal anti-androgen for prostate cancer

Crestor™ (rosuvastatin) Phase III for primary hypercholesterolaemia non-diabetic, non-atherosclerotic, metabolic syndrome patients with raised LDL-C

Entocort™ (budesonide) a glucocorticosteroid for inflammatory bowel diseases, Crohn's disease, and topical treatment of ulcerative colitis.

Faslodex™ (fulvestrant) is a hormonal treatment for hormone receptor-positive metastatic breast cancer in postmenopausal women whose disease has returned or progressed following antiestrogen therapy.

Iressa™ (gefitinib) an orally active EGFR tyrosine kinase inhibitor. It is currently available for the treatment of advanced non-small cell lung cancer (NSCLC)

Losec™ (omeprazole) and Nexium™ (esomeprazole) are acid pump inhibitors (also known as a proton pump inhibitor) for acid reflux syndrome.

Merrem™ (meropenem) is an ultra-broad spectrum injectable antibiotic for a wide variety of serious infections, including meningitis and pneumonia.

Oxis™ (formoterol) is a beta 2-agonist for asthma.

Seroquel™ (quetiapine) for schizophrenia and bipolar mania.

Zoladex™ (goserelin acetate) a luteinising hormone-releasing hormone analogue used to treat hormone-sensitive cancers of the prostate and breast (in pre-/perimenopausal women) and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning).

Zomig™ (zolmitriptan) an oral, selective 5-hydroxytryptamine receptor agonist or 'triptan' for acute treatment of migraine attacks