Sunday, October 14, 2007

AstraZeneca PIPELINE Part I


Note to self: A look at AZ's products and pipline:


Accolate™ (zafirlukast) Accolate™ (zafirlukast) an oral leukotriene receptor antagonist for the treatment of asthma

Arimidex™ (anastrozole) an aromatase inhibitor for use in postmenopausal women with hormone-sensitive early or advanced breast cancer.

Atacand™ (candesartan cilexetil) Phase III for diabetic retinopathy

Casodex™ (bicalutamide) an oral non-steroidal anti-androgen for prostate cancer

Crestor™ (rosuvastatin) Phase III for primary hypercholesterolaemia non-diabetic, non-atherosclerotic, metabolic syndrome patients with raised LDL-C

Entocort™ (budesonide) a glucocorticosteroid for inflammatory bowel diseases, Crohn's disease, and topical treatment of ulcerative colitis.

Faslodex™ (fulvestrant) is a hormonal treatment for hormone receptor-positive metastatic breast cancer in postmenopausal women whose disease has returned or progressed following antiestrogen therapy.

Iressa™ (gefitinib) an orally active EGFR tyrosine kinase inhibitor. It is currently available for the treatment of advanced non-small cell lung cancer (NSCLC)

Losec™ (omeprazole) and Nexium™ (esomeprazole) are acid pump inhibitors (also known as a proton pump inhibitor) for acid reflux syndrome.

Merrem™ (meropenem) is an ultra-broad spectrum injectable antibiotic for a wide variety of serious infections, including meningitis and pneumonia.

Oxis™ (formoterol) is a beta 2-agonist for asthma.

Seroquel™ (quetiapine) for schizophrenia and bipolar mania.

Zoladex™ (goserelin acetate) a luteinising hormone-releasing hormone analogue used to treat hormone-sensitive cancers of the prostate and breast (in pre-/perimenopausal women) and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning).

Zomig™ (zolmitriptan) an oral, selective 5-hydroxytryptamine receptor agonist or 'triptan' for acute treatment of migraine attacks

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